| Date | Home | Away | Result |
|---|---|---|---|
| 26/07/25 00:30 | New England Revolution | CF Montreal | 1-3 |
| Cancelled | Houston Dynamo | Los Angeles Galaxy | --- |
| 26/07/25 01:30 | FC Dallas | New York City FC | 3-4 |
| 26/07/25 01:40 | Columbus Crew | Orlando City | 1-3 |
| 26/07/25 03:30 | San Diego FC | Nashville SC | 1-0 |
| 26/07/25 03:30 | Los Angeles FC | Portland Timbers | 0-1 |
| 27/07/25 00:15 | Inter Miami CF | Cincinnati FC | 0-0 |
| 27/07/25 00:30 | Atlanta United FC | Seattle Sounders | 2-2 |
| 27/07/25 00:30 | Philadelphia Union | Colorado Rapids | 3-1 |
| 27/07/25 00:30 | D.C. United | Austin FC | 2-4 |
| 27/07/25 00:30 | Charlotte FC | Toronto FC | 2-0 |
| 27/07/25 01:30 | Chicago Fire | New York Red Bulls | 1-0 |
| 27/07/25 01:30 | St. Louis City SC | Minnesota United FC | 1-2 |
| 27/07/25 02:30 | Real Salt Lake | San Jose Earthquakes | 2-1 |
| 27/07/25 03:30 | Vancouver Whitecaps | Sporting Kansas City | 3-0 |