| Date | Home | Away | Result |
|---|---|---|---|
| 25/04/26 18:00 | Toronto FC | Atlanta United FC | 1-2 |
| 25/04/26 19:30 | CF Montreal | New York City FC | 1-0 |
| 25/04/26 21:45 | Minnesota United FC | Los Angeles FC | 0-1 |
| 26/04/26 00:30 | Cincinnati FC | New York Red Bulls | 2-0 |
| 26/04/26 00:30 | Inter Miami CF | New England Revolution | 1-1 |
| 26/04/26 00:30 | Columbus Crew | Philadelphia Union | 2-0 |
| 26/04/26 00:30 | D.C. United | Orlando City | 3-2 |
| 26/04/26 01:30 | Chicago Fire | Sporting Kansas City | 5-0 |
| 26/04/26 01:30 | Austin FC | Houston Dynamo | 2-0 |
| 26/04/26 01:40 | Nashville SC | Charlotte FC | 4-2 |
| 26/04/26 01:40 | St. Louis City SC | San Jose Earthquakes | 2-3 |
| 26/04/26 02:40 | San Diego FC | Portland Timbers | 1-2 |
| 26/04/26 03:30 | Vancouver Whitecaps | Colorado Rapids | 3-1 |
| 26/04/26 03:30 | Seattle Sounders | FC Dallas | 2-1 |
| 27/04/26 00:00 | Los Angeles Galaxy | Real Salt Lake | 2-1 |